Browsing Brage by Author "Wessel, Øystein"
Now showing items 1-11 of 11
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Comparison of transcriptome responses in blood cells of Atlantic salmon infected by three genotypes of Piscine orthoreovirus
Tsoulia, Thomais; Sundaram, Arvind; Amundsen, Marit Måsøy; Rimstad, Espen; Wessel, Øystein; Jørgensen, Jorunn B; Dahle, Maria Krudtå (Peer reviewed; Journal article, 2024)Piscine orthoreovirus (PRV) infection is common in aquaculture of salmonids. The three known PRV genotypes (PRV-1-3) have host species specificity and cause different diseases, but all infect and replicate in red blood ... -
Detection of Salmonid IgM Specific to the Piscine Orthoreovirus Outer Capsid Spike Protein Sigma 1 Using Lipid-Modified Antigens in a Bead-Based Antibody Detection Assay
Teige, Lena Hammerlund; Kumar, Subramani; Johansen, Grethe Marie; Wessel, Øystein; Vendramin, Niccoló; Lund, Morten; Rimstad, Espen; Boysen, Preben; Dahle, Maria (Peer reviewed; Journal article, 2019)Bead-based multiplex immunoassays are promising tools for determination of the specific humoral immune response. In this study, we developed a multiplexed bead-based immunoassay for the detection of Atlantic salmon (Salmo ... -
Dissemination of piscine orthoreovirus-1 (PRV-1) in atlantic salmon (salmo salar) during the early and regenerating phases of infection
Kannimuthu, Dhamotharan; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria K.; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Peer reviewed; Journal article, 2020)Piscine orthoreovirus-1 (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar), but the line of events from infection, pathologic change, and regeneration has not been ... -
Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection
Kannimuthu, Dhamotharan; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Peer reviewed; Journal article, 2020) -
Erythroid Progenitor Cells in Atlantic Salmon (Salmo salar) May Be Persistently and Productively Infected with Piscine Orthoreovirus (PRV)
Malik, Muhammad Salman; Bjørgen, Håvard; Kannimuthu, Dhamotharan; Wessel, Øystein; Koppang, Erling Olaf; Di Cicco, Emiliano; Hansen, Elisabeth Furuseth; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2019)Piscine orthoreovirus (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus targets erythrocytes in the acute peak phase, followed by cardiomyocytes, before the ... -
Implementation of mRNA–Lipid Nanoparticle Technology in Atlantic Salmon (Salmo salar)
Dahl, Lars Ole Sti; Hak, Sjoerd; Braaen, Stine; Molska, Alicja Anna; Rodà, Francesca; Parot, Jérémie; Wessel, Øystein; Fosse, Johanna Hol; Bjørgen, Håvard; Borgos, Sven Even F.; Rimstad, Espen (Peer reviewed; Journal article, 2024)Background: This study was conducted to investigate whether mRNA vaccine technology could be adapted for the ectothermic vertebrate Atlantic salmon (Salmo salar). Lipid nanoparticle (LNP) technology has been developed and ... -
Inactivation of Piscine orthoreovirus
Wessel, Øystein; Hansen, Elisabeth Furuseth; Løvoll, Marie; Inami, Makoto; Husby, Asbjørn; Kruse, Gesa; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2020) -
Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon
Malik, Muhammad Salman; Teige, Lena Hammerlund; Braaen, Stine; Olsen, Anne Berit; Nordberg, Monica; Amundsen, Marit; Kannimuthu, Dhamotharan; Svenning, Steingrim; Edholm, Eva-Stina Isabella; Takano, Tomokazu; Jørgensen, Jorunn; Wessel, Øystein; Rimstad, Espen; Dahle, Maria (Peer reviewed; Journal article, 2021)Heart and skeletal muscle inflammation (HSMI), caused by infection with Piscine orthoreovirus-1 (PRV-1), is a common disease in farmed Atlantic salmon (Salmo salar). Both an inactivated whole virus vaccine and a DNA vaccine ... -
Piscine orthoreovirus-1 isolates differ in their ability to induce heart and skeletal muscle inflammation in Atlantic salmon (Salmo salar)
Wessel, Øystein; Hansen, Elisabeth Furuseth; Dahle, Maria; Alarcon, Marta; Vatne, Nina Askim; Nyman, Ingvild Berg; Soleim, Karen Bækken; Kannimuthu, Dhamotharan; Timmerhaus, Gerrit; Markussen, Turhan Ali Dadasbilge; Lund, Morten; Aanes, Håvard; Devold, Magnus; Inami, Makoto; Løvoll, Marie; Rimstad, Espen (Peer reviewed; Journal article, 2020)Piscine orthoreovirus 1 (PRV-1) is the causative agent of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus is widespread in Atlantic salmon and was present in Norway long ... -
PRV-1 Infected Macrophages in Melanized Focal Changes in White Muscle of Atlantic Salmon (Salmo salar) Correlates With a Pro-Inflammatory Environment
Malik, Muhammad Salman; Bjørgen, Håvard; Nyman, Ingvild Berg; Wessel, Øystein; Koppang, Erling Olaf; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2021) -
Transcriptomics of early responses to purified Piscine orthoreovirus-1 in Atlantic salmon (Salmo salar L.) red blood cells compared to non-susceptible cell lines
Tsoulia, Thomais; Sundaram, Arvind Y. M.; Braaen, Stine; Jørgensen, Jorunn B; Rimstad, Espen; Wessel, Øystein; Dahle, Maria Krudtå (Peer reviewed; Journal article, 2024)