• Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein 

      Bian, Jifeng; Kim, Sehun; Kane, Sarah J.; Crowell, Jenna; Sun, Julianna L.; Christiansen, Jeffrey; Saijo, Eri; Moreno, Julie A.; DiLisio, James; Burnett, Emily; Pritzkow, Sandra; Gorski, Damian; Soto, Claudio; Kreeger, Terry J.; Balachandran, Aru; Mitchell, Gordon; Miller, Michael W.; Nonno, Romolo; Vikøren, Turid; Våge, Jørn; Madslien, Knut; Tran, Linh Dinh Thoai; Vuong, Tram Thu; Benestad, Sylvie Lafond; Telling, Glenn C. (Peer reviewed; Journal article, 2021)
      Prions are infectious proteins causing fatal, transmissible neurodegenerative diseases of animals and humans. Replication involves template-directed refolding of host encoded prion protein, PrPC, by its infectious conformation, ...
    • Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis 

      Deyab, Gia; Reine, Trine M.; Vuong, Tram Thu; Jenssen, Trond Geir; Hjeltnes, Gunnbjørg; Agewall, Stefan; Mikkelsen, Knut; Førre, Øystein; Fagerland, Morten; Kolset, Svein Olav; Hollan, Ivana (Peer reviewed; Journal article, 2021)
    • Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis 

      Deyab, Gia; Reine, Trine M.; Vuong, Tram Thu; Jenssen, Trond Geir; Hjeltnes, Gunnbjørg; Agewall, Stefan; Mikkelsen, Knut; Førre, Øystein; Fagerland, Morten; Kolset, Svein Olav; Hollan, Ivana (Peer reviewed; Journal article, 2021)
      The endothelial glycocalyx (EG) is essential for proper function of the endothelium and for vascular integrity, but its role in premature atherogenesis in rheumatoid arthritis (RA) has not been studied yet. EG impairment ...
    • Goats naturally devoid of PrPC are resistant to scrapie 

      Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)
    • Goats naturally devoid of PrPC are resistant to scrapie 

      Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)
      Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the "protein-only" hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological ...