Browsing Brage by Author "Benestad, Sylvie Lafond"
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Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein
Bian, Jifeng; Kim, Sehun; Kane, Sarah J.; Crowell, Jenna; Sun, Julianna L.; Christiansen, Jeffrey; Saijo, Eri; Moreno, Julie A.; DiLisio, James; Burnett, Emily; Pritzkow, Sandra; Gorski, Damian; Soto, Claudio; Kreeger, Terry J.; Balachandran, Aru; Mitchell, Gordon; Miller, Michael W.; Nonno, Romolo; Vikøren, Turid; Våge, Jørn; Madslien, Knut; Tran, Linh Dinh Thoai; Vuong, Tram Thu; Benestad, Sylvie Lafond; Telling, Glenn C. (Peer reviewed; Journal article, 2021)Prions are infectious proteins causing fatal, transmissible neurodegenerative diseases of animals and humans. Replication involves template-directed refolding of host encoded prion protein, PrPC, by its infectious conformation, ... -
Chronic wasting disease associated with prion protein gene (PRNP) variation in Norwegian wild reindeer (Rangifer tarandus)
Guere Calderon, Mariella Evelyn; Våge, Jørn; Tharaldsen, Helene; Benestad, Sylvie Lafond; Vikøren, Turid; Madslien, Knut Ivar Engesæter; Hopp, Petter; Rolandsen, Christer Moe; Røed, Knut; Tranulis, Michael A. (Peer reviewed; Journal article, 2020)The emergence of CWD in Europe in 2016 and the first natural infection in wild reindeer warranted disease management. This led to the testing of 2424 hunted or culled reindeer during 2016–2018, from the infected subpopulation ... -
Effect of feed additives as alternatives to in-feed antimicrobials on production performance and intestinal Clostridium perfringens counts in broiler chickens
Granstad, Silje; Kristoffersen, Anja Bråthen; Benestad, Sylvie Lafond; Sjurseth, Siri Kulberg; David, Bruce; Sørensen, Line; Fjermedal, Arnulf; Edvardsen, Dag Henning; Sanson, Gorm; Løvland, Atle; Kaldhusdal, Magne (Peer reviewed; Journal article, 2020) -
Goats naturally devoid of PrPC are resistant to scrapie
Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020) -
Goats naturally devoid of PrPC are resistant to scrapie
Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the "protein-only" hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological ... -
The demographic pattern of infection with chronic wasting disease in reindeer at an early epidemic stage
Mysterud, Atle; Madslien, Knut Ivar Engesæter; Viljugrein, Hildegunn; Vikøren, Turid; Andersen, Roy; Guere Calderon, Mariella Evelyn; Benestad, Sylvie Lafond; Hopp, Petter; Strand, Olav; Ytrehus, Bjørnar; Røed, Knut; Rolandsen, Christer Moe; Våge, Jørn (Peer reviewed; Journal article, 2019)Infection patterns linked to age and sex are crucial to predict the population dynamic effects of diseases in long-lived species. How such demographic patterns of infection arise is often multifactorial, although the cause ...